Quinone and hydroquinone lipids
Medchemexpress LLC Oxytocin acetate | 6233-83-6 | 99.66% | 1067.2 g/mol | 5 MG
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. It can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects, especially in the face of adversity or trauma.
- Known for facilitating parturition, lactation, and prosocial behaviors
- Functions as a stress-coping molecule
- Offers anti-inflammatory, antioxidant, and protective effects
Medchemexpress LLC Abiraterone acetate (Standard) | 154229-18-2 | 99.8% | C₂₆H₃₃NO₂ | 5 MG
Abiraterone acetate (Standard) is the analytical standard of Abiraterone acetate, intended for research and analytical applications. It is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity, and is a proagent form of Abiraterone. This compound is used as a reference standard supplied assay.
- Intended for research and analytical applications
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments in HPLC, GC, and MS
Medchemexpress LLC DT-2 acetate | 98.6% | 3761.25 | 5 MG
DT-2 acetate is identified as a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG). This compound effectively inhibits PKG-catalyzed phosphorylation, with a Ki value of 12.5 nM. It is designated for research applications only.
- Potent and selective inhibition of cGMP-dependent protein kinase.
- Inhibits phosphorylation with a Ki of 12.5 nM.
- Suitable for research applications.
- High purity of 98.64%.
- Available as a white to off-white solid.
- Related to peptides and derivatives, and inhibitors and substrates.
- Referenced in scientific literature.
Medchemexpress LLC Delmitide acetate | 501019-16-5 | 99.2% | 1288.62 g/mol | C59H105N17O11.C2H4O2 | 5 MG
Delmitide acetate is an orally active D-isomer decapeptide with potent anti-inflammatory activity. It inhibits production of TNF-α, IFN-γ, and IL-12, and up-regulates heme oxygenase-1, making it useful for preclinical studies such as ulcerative colitis and cytokine modulation research.
- Orally active d-isomer decapeptide.
- Inhibits pro-inflammatory cytokines, including TNF-α, IFN-γ, and IL-12.
- Up-regulates heme oxygenase-1 to modulate inflammatory response.
- Suitable for ulcerative colitis and inflammation studies.
- Provided as an acetate salt in small research quantities.
- High purity suitable for preclinical research.
Cayman Chemical VItamIn K1 2 3-epoxIde 500ug
The inactive metabolite of vitamin K1 formed during blood clotting that is rapidly reduced back to vitamin K1 by a microsomal epoxide reductase
Medchemexpress LLC Vitamin D Receptor/V 5ug
Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
Medchemexpress LLC Alisol B 23-acetate | 26575-95-1 | 514.74 | 25 MG
Alisol B 23-acetate | 26575-95-1 | 514.74 | 25 MG
Medchemexpress LLC rel-VU6021625 | 2307718-96-1 | 99.67% | 432.56 | 25 MG
rel-VU6021625 is the relative configuration of VU6021625. VU6021625 is identified as a potent and selective mAChR M4 antagonist, exhibiting IC50 values of 0.44 nM for human M4 and 57 nM for rat M4. The product is intended for research use only.
- Potent and selective mAChR M4 antagonist
- Relative configuration of VU6021625
- IC50 values: 0.44 nM (human M4), 57 nM (rat M4)
Medchemexpress LLC Resomelagon acetate (AP1189 acetate) | 1809420-72-1 | MFCD00000305 | 99.8% | 358.35 | 5 MG
Resomelagon acetate (AP1189 acetate) is a potent, orally active melanocortin receptor (MR) agonist, specifically targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, exhibiting anti-inflammatory activity. This compound is applicable for research in obesity and chronic inflammation.
- Potent, orally active melanocortin receptor agonist
- Specifically targets MC1 and MC3
- Induces ERK1/2 phosphorylation and Ca2+ mobilization
- Exhibits anti-inflammatory activity
- Inhibits TNF-α release and efferocytosis
- Promotes resolution of acute inflammation
- Reduces arthritis in mice
Medchemexpress LLC Abiraterone acetate | 154229-18-2 | 99.91% | C26H33NO2 | 5 MG
Abiraterone acetate is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. It is a proagent form of Abiraterone.
- Oral administration
- Potent, selective, and irreversible inhibitor of CYP17A1
- Exhibits antiandrogen activity
- Prodrug form of Abiraterone
- Inhibits 17,20-lyase and 17α-hydroxylase activity
- Inhibits proliferation of AR-positive prostate cancer cell lines
- Blocks synthesis of 5α-dione and DHT
- Inhibits CRPC progression
- Prolongs survival in castration-resistant prostate cancer (CRPC)
- Inhibits dehydroepiandrosterone (DHEA) depletion and Δ4-androstenedione (AD) accumulation
Medchemexpress LLC Alarelin Acetate | 79561-22-1 | 99.7% | 1287.42 | 5 MG
Alarelin Acetate is a synthetic GnRH agonist. It significantly lowers cell viability and achieves a maximum stimulatory effect on cell viability at a concentration of 10-5 M, acting in a dose-dependent manner. It can inhibit gastric acid secretion by directly acting on parietal cells in rats and by inhibiting vagous function, and can also significantly enhance the ratio of the G1 phase and decrease the ratio of the S phase of GSMC of rats.
- Synthetic GnRH agonist.
- Lowers cell viability significantly.
- Inhibits gastric acid secretion.
- Enhances G1 phase and decreases S phase in rat GSMC.
- For research use only.
- Not sold to patients.
Medchemexpress LLC Linaclotide (acetate) | 851199-60-5 | 98.6% | 1586.79 | 5 MG
Linaclotide acetate is a potent and selective guanylate cyclase C agonist, developed to address conditions such as constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. It functions by activating guanylate cyclase C, which helps to regulate fluid secretion and gastrointestinal transit. This compound is intended for research purposes only and is not sold to patients.
- Potent and selective guanylate cyclase C agonist.
- Developed for treating constipation-predominant irritable bowel syndrome.
- Developed for treating chronic constipation.
- Available in various quantities for research needs.
- High purity of 98.61% ensures reliable experimental results.
- Detailed documentation including data sheet, COA, and SDS is provided.
- Solubility information and preparation protocols are available for in vitro and in vivo studies.
- Supported by scientific publications.
Medchemexpress LLC Vitamin K5 (hydrochloride) | 130-24-5 | 25 MG
Vitamin K5 hydrochloride is a photosensitizer and an antimicrobial agent that functions as a specific PKM2 inhibitor. It is suitable for research related to infection and cancer, and can also be used as a preservative for pharmaceuticals, foods, and beverages.
- Acts as a specific PKM2 inhibitor
- Induces apoptosis in colon 26 cells
- Increases antibacterial effects of UVA irradiation against various bacteria
- Generates superoxide anion radical and hydroxyl radical
- Inhibits cellular glucose consumption and lactate production
- Suppresses the proliferation of colon 26 cells
- Induces cell apoptosis and increases caspase-3 activity in colon 26 cells
Medchemexpress LLC Macupatide acetate | 99.7% | 4984.60 | 25 MG
Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. It is used in the research of type 2 diabetes by improving insulin secretion responses and insulin sensitivity. Preclinical studies suggest it reduces body weight and fasting blood glucose.
- Improves insulin secretion responses
- Improves insulin sensitivity
- Produces larger insulin sensitivity improvement compared to selective GLP-1 RA dulaglutide
- Combination therapy with GLP-1 RA dulaglutide had additive effects on insulin sensitivity
- Reduces body weight in patients with type 2 diabetes
- Reduces fasting blood glucose in patients with type 2 diabetes
Medchemexpress LLC Bradykinin acetate | 6846-03-3 | 99.6% | 1060.21 (free base) | 25 MG
Bradykinin acetate | 6846-03-3 | 99.6% | 1060.21 (free base) | 25 MG